Search results for "Medicagenic acid"

showing 3 items of 3 documents

2002

by Mohamed Elbandya), Tomofumi Miyamotob), Cle¬ment Delaudec), and Marie-Aleth Lacaille-Dubois*a) a) Laboratoire de Pharmacognosie, Unite¬ de Mole¬cules d×Inte¬re√ t Biologique (UMIB JE 2244), Faculte¬ de Pharmacie, Universite¬ de Bourgogne, 7 Bd Jeanne d×Arc, BP 87900, F-21079 Dijon Cedex b) Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan c) Centre de Recherche Phytochimique, Universite¬ de Lieige, Institut de Chimie-B6, Sart Tilman B-4000-Lieige I

Inorganic ChemistryStereochemistryChemistryMuraltia ononidifoliaOrganic ChemistryDrug DiscoveryPhysical and Theoretical ChemistryBiochemistryCatalysisMedicagenic acidHelvetica Chimica Acta
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Acylated oleanane-type saponins from Ganophyllum giganteum

2014

Abstract Five oleanane-type saponins , 3- O -β- D -glucuronopyranosylzanhic acid 28- O -β- D -xylopyranosyl-(1→3)-[α- L -rhamnopyranosyl-(1→2)]-(4- O -acetyl)-β- D -fucopyranosyl ester ( 1 ), 3- O -β- D -glucopyranosylzanhic acid 28- O -β- D -xylopyranosyl-(1→3)-[α- L -rhamnopyranosyl-(1→2)]-(4- O -acetyl)-β- D -fucopyranosyl ester ( 2 ), zanhic acid 28- O -β- D -xylopyranosyl-(1→3)-[α- L -rhamnopyranosyl-(1→2)]-(4- O -acetyl)-β- D -fucopyranosyl ester ( 3 ), zanhic acid 28- O -α- L -rhamnopyranosyl-(1→2)-4- O -[(3′-hydroxy-2′-methyl-butyroyloxy)-3-hydroxy-2-methyl-butyroyloxy]-β- D -fucopyranosyl ester ( 4 ), medicagenic acid 28- O -α- L -rhamnopyranosyl-(1→2)-4- O -[(3′-hydroxy-2′-methyl-…

StereochemistryAcylationMolecular ConformationPlant ScienceHorticulturePlant RootsBiochemistryMiceStructure-Activity Relationshipchemistry.chemical_compoundSapindaceaeCell Line TumorAnimalsHumansOrganic chemistryMoietyOleanolic AcidMolecular BiologyOleananeCell ProliferationInflammationBiological ProductsDose-Response Relationship DrugChemistryHydrolysisAnti-Inflammatory Agents Non-SteroidalGeneral MedicineSaponinsAntineoplastic Agents PhytogenicMedicagenic acidDoratoxyleaeDrug Screening Assays AntitumorPhytochemistry
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Three New Medicagenic Acid Saponins from Polygala micranthaGuill. & Perr.

2011

Three new medicagenic acid saponins, micranthosides A–C (1–3), were isolated from the roots of Polygala micranthaGuill. & Perr., along with six known presenegenin saponins. Their structures were elucidated on the basis of extensive 1D- and 2D-NMR experiments (1H, 13C, DEPT, COSY, TOCSY, NOESY, HSQC, and HMBC) and mass spectrometry as 3-O-β-D-glucopyranosylmedicagenic acid 28-[O-β-D-galactopyranosyl-(14)-O-β-D-xylopyranosyl-(14)-O-α-L-rhamnopyranosyl-(12)-β-D-fucopyranosyl] ester (1), 3-O-β-D-glucopyranosylmedicagenic acid 28-[O-6-O-acetyl-β-D-galactopyranosyl-(14)-O-β-D-xylopyranosyl-(14)-O-α-L-rhamnopyranosyl-(12)-β-D-fucopyranosyl] ester (2), and 3-O-{O-β-D-glucopyranosyl-(13)-O-[β-D-gluc…

biologyChemistryStereochemistryOrganic ChemistryDEPTMass spectrometrybiology.organism_classificationBiochemistryCatalysisPolygalaMedicagenic acidInorganic ChemistryHuman colon cancerDrug DiscoveryPhysical and Theoretical ChemistryCytotoxicityTwo-dimensional nuclear magnetic resonance spectroscopyHeteronuclear single quantum coherence spectroscopyHelvetica Chimica Acta
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